| Form 144 Filer Information |
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144
NOTICE OF PROPOSED SALE OF SECURITIES
PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933 | |
FORM 144/A |
| Filer CIK | 0002108105 |
| Filer CCC | XXXXXXXX |
| Previous Accession Number Of The Filing | 0002108105-26-000001 |
| Is this a LIVE or TEST Filing? |  LIVE
 TEST
|
Submission Contact Information | |
| Name | |
| Phone | |
| E-Mail Address |
| Name of Issuer | Adagene Inc. |
| SEC File Number | 001-39997 |
| Address of Issuer | 4F, BUILDING C14, NO. 218, XINGHU STREET SUZHOU INDUSTRIAL PARK SUZHOU CHINA 215123 |
| Phone | 86-512-87773632 |
| Name of Person for Whose Account the Securities are To Be Sold | Adagene Inc. |
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account
the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given
as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales
for the account of the person filing this notice.
| |
| Relationship to Issuer | Officer |
| Title of the Class of Securities To Be Sold | Name and Address of the Broker | Number of Shares or Other Units To Be Sold | Aggregate Market Value | Number of Shares or Other Units Outstanding | Approximate Date of Sale | Name the Securities Exchange |
|---|---|---|---|---|---|---|
| ADS EACH REPRESENTING 1.25 ORDINARY SHARES, SOLD TO COVER COST | Futu SecuritiesInternational (HongKong) Ltd 34/F, United Centre 95 Queensway Admiralty K3 000000 | 40000 | 158000.00 | 67143344 | 08/21/2026 | NASDAQ |
| ADS EACH REPRESENTING 1.25 ORDINARY SHARES, SOLD TO COVER COST | Futu SecuritiesInternational (HongKong) Ltd 34/F, United Centre 95 Queensway Admiralty K3 000000 | 40000 | 158000.00 | 67143344 | 08/24/2026 | NASDAQ |
| ADS EACH REPRESENTING 1.25 ORDINARY SHARES, SOLD TO COVER COST | Futu SecuritiesInternational (HongKong) Ltd 34/F, United Centre 95 Queensway Admiralty K3 000000 | 40000 | 158000.00 | 67143344 | 08/25/2026 | NASDAQ |
| ADS EACH REPRESENTING 1.25 ORDINARY SHARES, SOLD TO COVER COST | Futu SecuritiesInternational (HongKong) Ltd 34/F, United Centre 95 Queensway Admiralty K3 000000 | 11000 | 43450.00 | 67143344 | 08/26/2026 | NASDAQ |
| Title of the Class | Date you Acquired | Nature of Acquisition Transaction | Name of Person from Whom Acquired | Is this a Gift? | Date Donor Acquired | Amount of Securities Acquired | Date of Payment | Nature of Payment * |
|---|---|---|---|---|---|---|---|---|
| ADS EACH REPRESENTING 1.25 ORDINARY SHARES, SOLD TO COVER COST | 08/21/2026 | VESTING OF OPTIONS GRANTED PURSUANT TO ISSUER ESOP PLAN | Adagene Inc. |  | 40000 | 08/21/2026 | VESTING OF OPTIONS | |
| ADS EACH REPRESENTING 1.25 ORDINARY SHARES, SOLD TO COVER COST | 08/24/2026 | VESTING OF OPTIONS GRANTED PURSUANT TO ISSUER ESOP PLAN | Adagene Inc. | | 40000 | 08/24/2026 | VESTING OF OPTIONS | |
| ADS EACH REPRESENTING 1.25 ORDINARY SHARES, SOLD TO COVER COST | 08/25/2026 | VESTING OF OPTIONS GRANTED PURSUANT TO ISSUER ESOP PLAN | Adagene Inc. | | 40000 | 08/25/2026 | VESTING OF OPTIONS | |
| ADS EACH REPRESENTING 1.25 ORDINARY SHARES, SOLD TO OVER COST | 08/26/2026 | VESTING OF OPTIONS GRANTED PURSUANT TO ISSUER ESOP PLAN | Adagene Inc. | | 11000 | 08/26/2026 | VESTING OF OPTIONS |
| Name and Address of Seller | Title of Securities Sold | Date of Sale | Amount of Securities Sold | Gross Proceeds |
|---|---|---|---|---|
| CHUNFANG GU 4F, Building C14, No. 218 Xinghu Street, Suzhou Industrial Park Suzhou, Jiangsu Province F4 215123 | ADS | 07/28/2026 | 475 | 1634.19 |
| Remarks | The securities set forth herein are being sold pursuant to a sell-to-cover arrangement to satisfy the cost including tax withholding obligations arising in connection with the vesting of the options. |
| Date of Notice | 08/20/2026 |
ATTENTION: | |
| The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date. | |
| Signature | /s/ CHUNFANG GU |
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001) | |
